# Suicide by Firearm and Hormonal Imbalances: A Forensic Case Report With Literature Review

**Authors:** Saverio Gualtieri, Matteo Antonio Sacco, Maria Cristina Verrina, Chara Spiliopoulou, Isabella Aquila

PMC · DOI: 10.7759/cureus.79803 · 2025-02-27

## TL;DR

This paper explores the connection between uterine fibroids, hormonal imbalances, and mental health issues like depression and suicidal thoughts.

## Contribution

The paper reviews existing literature to highlight the potential link between uterine fibroids and psychiatric disorders.

## Key findings

- Uterine fibroids are common in women and can cause physical and emotional distress.
- Hormonal imbalances associated with fibroids may contribute to mental health issues.
- Psychological support is important for women dealing with fibroid-related anxiety and depression.

## Abstract

Hormonal imbalances play a crucial role in the development of various diseases, with a significant impact on the gynecological system, especially in the onset of uterine fibroids (UFs). UFs, also known as myomas or leiomyomas, are noncancerous uterine growths commonly observed in women, particularly during their reproductive years. By age 50, many women experience fibroids, though the condition's prevalence varies significantly across different ethnic groups. While most fibroids remain asymptomatic, those that are symptomatic can lead to several issues, such as irregular bleeding, pelvic discomfort, and complications during pregnancy.

Receiving a diagnosis of fibroids can be distressing, particularly when concerns arise about their potential link to more serious conditions. This distress can adversely affect a woman's quality of life and mental health, sometimes contributing to emotional distress, depressive symptoms, or even suicidal ideation. The management of UFs encompasses a spectrum of approaches, from careful monitoring to medical or surgical interventions, which are chosen based on the severity of symptoms and the patient’s preferences. Psychological support can be valuable in helping women manage the anxiety and fears associated with the diagnosis and treatment process. Consequently, the impact of UFs on women's mental health warrants attention. This paper aims to review the existing scientific literature on the potential link between UFs, hormonal imbalances, and an increased risk of psychiatric disorders.

## Full-text entities

- **Diseases:** myomas (MESH:D009214), psychiatric disorders (MESH:D001523), anxiety (MESH:D001007), depressive symptoms (MESH:D003866), bleeding (MESH:D006470), UFs (MESH:D007889)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11955573/full.md

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Source: https://tomesphere.com/paper/PMC11955573