# A Case of Diffuse B-Cell Lymphoma Presenting as a Rash on the Chest and Abdomen

## TL;DR

A rare case of lymphoma presented as a rash on the chest and abdomen, complicating the diagnosis during sepsis treatment.

## Contribution

Highlights a rare presentation of DLBCL as a rash in unusual locations during sepsis treatment.

## Key findings

- DLBCL presented as a rash on the upper chest, shoulder, and abdomen.
- The rash developed while the patient was being treated for sepsis.
- The case was complicated by the possibility of a drug-induced rash.

## Abstract

Diffuse large B-cell lymphoma (DLBCL) can present with skin manifestations either as a primary cutaneous DLBCL or as systemic DLBCL with cutaneous manifestations. The majority of cutaneous cases present with erythematous nodules on the legs, most commonly the lower legs. DLBCL presenting at a cutaneous site can be mistaken for cellulitis, a chronic venous ulcer, or psoriasis. Here, we present a case of DLBCL manifesting as a rash on the upper chest, shoulder, and abdomen. The case is notable in the fact that the rash developed while the patient was hospitalized and being treated for sepsis, with a drug-induced rash being a confounding diagnosis.