# Unraveling the Complexity of Non-typhoidal Salmonella Genitourinary Infection in HIV: A Case Report and Management Strategy

## TL;DR

This case report details a rare non-typhoidal Salmonella infection in an HIV-positive man and outlines its management.

## Contribution

The paper presents a unique case of Salmonella UTI in an HIV patient and emphasizes the need for targeted treatment.

## Key findings

- Non-typhoidal Salmonella was identified in urine and blood cultures of an HIV-positive patient.
- Treatment required at least 14 days of antibiotics and repeat urine cultures for confirmation.
- Antibiotic resistance highlights the importance of local sensitivity data in treatment planning.

## Abstract

Salmonella urinary tract infections (UTIs) are rare and typically affect immunocompromised or anatomically predisposed individuals. While usually foodborne, transmission can also occur from pets or person to person. Symptoms mimic common UTIs and may present with or without prior gastrointestinal illness. We report the case of a 56-year-old HIV-positive male with poor medication compliance who presented with altered mental status and burning micturition. Urine and blood cultures revealed non-typhoidal Salmonella, prompting targeted antibiotic therapy. Treatment involves at least 14 days of antibiotics, with repeat urine cultures to ensure eradication. Rising antibiotic resistance necessitates awareness of local sensitivity patterns.