# Effect of strip type denture adhesives on Candida species colonization in complete denture wearing patients

## TL;DR

This study found that using strip-type denture adhesives for 14 days did not significantly affect Candida colonization in complete denture users.

## Contribution

The study provides new evidence on the safety of strip denture adhesives regarding Candida colonization in edentulous patients.

## Key findings

- No significant difference in Candida colonization was observed between the control and test groups.
- Strip denture adhesive use was found to be safe for complete denture wearers over 14 days.

## Abstract

The present study was planned to evaluate the influence of strip of denture adhesive on oral microflora, mainly Candida
species in the participants who were instructed to use Super Polygrip Comfort Seal Strips denture adhesive for 14 days of trial
period. 24 completely edentulous patients treated with complete denture were randomly divided into following - Control and Test group
(12 each group). Test group was prescribed a strip denture adhesive and instructed to use it for 14 days. Samples of saliva were
collected from all participants (both control and test groups) on 0 day, 7th and 14th day. Collected samples were diluted with standard
protocol and coated on culture media of Sabouraud dextrose agar and incubated for 48 hours at 37°C. The CFU/ml was analyzed from
both groups. Collected data then analyzed statistically with Mann - Whitney U - Test where α kept at ≤ 5%. No significant
statistical difference was found between the control and the test group after the testing duration of 14 days. Thus, results suggested
that strip denture adhesive did not have any influence on the colonization of Candida species during 14 days of test
period and it is safe for the use in complete denture wearing patients.