# Neuroendocrine carcinoma causing common bile duct obstruction: a case report

## TL;DR

A 46-year-old man with no health issues was diagnosed with a rare neuroendocrine tumor near his bile duct, causing jaundice and liver issues.

## Contribution

This case report highlights the rare occurrence of neuroendocrine carcinoma in the periampullary region and its clinical presentation.

## Key findings

- A hypo-enhancing periampullary mass was found to cause bile duct obstruction and jaundice.
- Histopathology confirmed poorly differentiated neuroendocrine carcinoma.
- The patient was lost to follow-up, limiting further treatment insights.

## Abstract

A 46-year-old male with no comorbidities was referred to our hospital because of jaundice and elevated LFT markers. After further investigations, he underwent magnetic resonance cholangiopancreatography (MRCP), which revealed a hypo-enhancing periampullary mass measuring 15 mm in size causing common bile duct (CBD) dilatation of 12 mm in cross diameter with intrahepatic biliary obstruction, which explained the patient’s symptoms. Side-view endoscopy was performed to obtain a specimen of the mass. Further histopathological workup revealed poorly differentiated neuroendocrine carcinoma (NEC). A multidisciplinary team (MDT) was conducted, and the patient was planned to undergo positron emission tomography-computed tomography (PET-CT) scan to investigate any further organ metastasis. Unfortunately, the patient missed his upcoming appointments and was lost to follow-up. Nevertheless, more research is needed to understand pathogenesis and the best course of management for small periampullary NETs.