# Spindle Cell Rhabdomyosarcoma of the Hand in a Full-Term Newborn: A Case Report

## TL;DR

A rare case of spindle cell rhabdomyosarcoma in a newborn's hand is reported, highlighting its unusual presentation and poor prognosis.

## Contribution

This case report presents a rare instance of spindle cell RMS in a full-term newborn's hand with lymph node involvement.

## Key findings

- The tumor was diagnosed as stage IRS 3 spindle cell RMS based on histopathology.
- The patient underwent surgery and chemotherapy but died from treatment complications.
- The case exhibits unusual features including age, gender, site, and poor outcome.

## Abstract

Rhabdomyosarcoma (RMS) is a rare soft tissue tumor with the most common sites of origin in the genitourinary tract, head, and neck regions, and extremities are less commonly involved. Spindle cell RMS is a rare variant of RMS in infants. RMS is uncommon in the hand. We present a case of spindle cell RMS in the hand of a full-term female newborn with regional lymph node involvement. Based on histopathology, the diagnosis of spindle cell RMS was made in stage IRS 3 of the Intergroup Rhabdomyosarcoma Study Group (IRSG) staging system. The infant underwent complete surgical resection and axillary lymph node removal, followed by chemotherapy. She died from complications of chemotherapy a year after initiation of treatment. The age, gender, poor outcome, and site are unusual features for this type of RMS.