# Uncomplicated pharyngitis due to family transmission of hypervirulent Klebsiella pneumoniae

## TL;DR

A family experienced throat infections from a highly virulent strain of Klebsiella pneumoniae, highlighting its possible spread within households.

## Contribution

The study reveals household transmission of hvKp through respiratory routes and suggests improved screening methods for early detection.

## Key findings

- Two family members had genetically identical hvKp infections, indicating household transmission.
- Nasopharyngeal carriage and droplets may be key in spreading hvKp.
- Routine screening and genotyping can aid in early hvKp diagnosis.

## Abstract

We describe two cases of uncomplicated pharyngitis caused by hypervirulent Klebsiella pneumoniae (hvKp) in a family, initially in an immunocompetent adolescent, followed by possible household spread resulting in similar presentations in the patient’s parent. Genomic analysis confirmed hvKp from the two cases were genetically identical and typed as K2-ST3252. Nasopharyngeal carriage and respiratory secretion/droplet may play an important yet underrecognized role in the transmission of hvKp. Enhancing routine screening for hvKp in the upper respiratory culture, followed by genotyping provides an effective pathway for early diagnosis.