# Demographic Factors and Aortic Stenosis-Related Death Locations: A Cross-Sectional Analysis

**Authors:** Adam Bacon, Hesham Abdalla, Ramzi Ibrahim, Mohamed Allam, Maryam Emami Neyestanak, Ghee Kheng Lim, Xuan Ci Mee, Hoang Nhat Pham, Mahmoud Abdelnabi, Justin Z. Lee, Juan Farina, Chadi Ayoub, Reza Arsanjani, Kwan Lee

PMC · DOI: 10.3390/jcm14061969 · Journal of Clinical Medicine · 2025-03-14

## TL;DR

This study explores how demographic factors affect where aortic stenosis patients die in the US, highlighting disparities and the need for equitable care.

## Contribution

The study identifies specific demographic associations with death locations for aortic stenosis patients, offering insights for targeted interventions.

## Key findings

- Black and Hispanic individuals had higher odds of dying in inpatient facilities compared to White individuals.
- Higher education levels were linked to increased odds of dying at home and decreased odds of hospice/nursing facility death.
- Those aged >85 years were more likely to die at home or in hospice/nursing facilities.

## Abstract

Background: Aortic stenosis (AS) imposes a significant mortality burden. Understanding demographic influences on the location of AS-related death is crucial for advancing equitable end-of-life care. Therefore, we investigated how demographic factors influence the location of death among AS patients in the United States. Methods: We completed a cross-sectional study utilizing US mortality data from the CDC’s WONDER database for 2019. All files related to decedents with AS identified as the primary cause of death were obtained, including demographic information and death locations (i.e., inpatient facilities, outpatient/ER facilities, home, or hospice/nursing facilities). Associations between demographic factors (age, sex, race/ethnicity, marital status, and education) and place of death were assessed using multivariable logistic regression models, yielding odds ratios (ORs). Results: In 2019, most AS-related deaths occurred in inpatient facilities (38.3%, n = 5062), home (29.2%, n = 3859), or hospice/nursing facilities (28.6%, n = 3775). Higher odds of inpatient death were observed among Black (OR 1.67, p < 0.001) and Hispanic individuals (OR 1.91, p < 0.001) compared to White decedents. Those aged >85 years were more likely to die at home (OR 1.76, p < 0.001) or in hospice/nursing facilities (OR 7.80, p < 0.001). Males had increased odds of inpatient death (OR 1.09, p = 0.044) but decreased odds of hospice/nursing facility death (OR 0.87, p = 0.003). Higher education levels were associated with increased odds of home death (OR 1.33, p = 0.023) and decreased odds of hospice/nursing facility death (OR 0.71, p = 0.015). Conclusions: Demographic factors significantly influence the location of death among AS patients, emphasizing the need for culturally and socioeconomically tailored interventions to promote equitable end-of-life care.

## Linked entities

- **Diseases:** aortic stenosis (MONDO:0042981)

## Full-text entities

- **Diseases:** Related Death (MESH:D003643), AS (MESH:D001024)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## References

29 references — full list in the complete paper: https://tomesphere.com/paper/PMC11942866/full.md

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Source: https://tomesphere.com/paper/PMC11942866