# Pilot Study on the Effect of Cannabidiol-Coated Fabric for Pillow Covers Improves the Sleep Quality of Shift Nurses

**Authors:** Mashita Afzal, Chieh-Liang Huang, Shih-Hao Huang, Chia-Ing Li, Wen-Chun Liao, Juan-Cheng Yang, Wen-Lung Ma

PMC · DOI: 10.3390/healthcare13060585 · Healthcare · 2025-03-07

## TL;DR

A pilot study found that using a cannabidiol (CBD)-coated pillow cover improved sleep quality and reduced anxiety in shift nurses.

## Contribution

This study explores the novel use of CBD-coated fabric as a non-ingestible method to improve sleep quality.

## Key findings

- CBD-coated pillow covers led to improved subjective sleep quality in 7.3% of participants.
- Anxiety levels significantly decreased among participants using the CBD-coated pillow covers.
- Light and deep sleep durations showed modest increases, though not statistically significant.

## Abstract

Background: Sleep difficulty is common in the current society. Poor sleep has a significant influence on health, social interactions and even mortality; therefore, maintaining good sleep is of prime importance. Cannabidiol (CBD), a cannabis-derived compound, is known for its medical significance with many positive effects in humans, including decreasing anxiety and improving sleep for those with sleep disorders. Objective: However, whether CBD skin absorption results in similar effects is unknown. Therefore, examining CBD-coated fabric as a pillow cover to improve sleep quality in duty shift nurses is the purpose of this paper. Methods: This study recruited 55 duty shift nurses as participants to evaluate sleep patterns and quality using the Pittsburgh Sleep Quality Index (PSQI) and a consumer-grade tracker (Fitbit Charge 3). Data were collected over three phases: a one-week baseline period, a two-week intervention period using a CBD-coated pillow cover and a one-week follow-up period, referred to as the post-intervention phase, during which the use of CBD-coated pillow cover was continued. Results: Of the 55 participants, 10 were men (18.2%) and 45 were women (81.8%). At baseline, all participants exhibited poor sleep quality (PSQI ≥ 5). However, after three weeks of using CBD-coated pillow covers, subjective sleep quality significantly improved, with 7.3% of participants achieving PSQI scores <5. Additionally, slight changes in sleep patterns were observed, with increases in both light sleep and deep sleep durations. Light sleep duration increased from a baseline of 196.21 ± 65.28 to 206.57 ± 59.15 min two weeks after intervention (p = 0.337). Similarly, deep sleep duration showed a modest increase from 61.97 ± 21.01 min to 64.35 ± 22.19 min (p = 0.288). Furthermore, a significant reduction in anxiety levels was reported (p < 0.005). Conclusions: Using a CBD-coated pillow cover was found to enhance sleep duration in healthy individuals experiencing poor sleep. Consequently, for adults struggling with sleep difficulties, incorporating a CBD-coated pillow cover may serve as an effective aid in improving sleep quality.

## Linked entities

- **Chemicals:** Cannabidiol (PubChem CID 644019), CBD (PubChem CID 644019)

## Full-text entities

- **Diseases:** Sleep difficulty (MESH:D012893), anxiety (MESH:D001007)
- **Chemicals:** CBD (MESH:D002185)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC11942488/full.md

## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11942488/full.md

## References

33 references — full list in the complete paper: https://tomesphere.com/paper/PMC11942488/full.md

---
Source: https://tomesphere.com/paper/PMC11942488