# Investigating attitudes towards medication and barriers to self-management among Hungarian adults with diabetes mellitus: A cross-sectional study

**Authors:** Klára Bíró, Mihály Varga, Viktor Dombrádi, Nóra Kovács, Attila Nagy, Gábor Bányai, Klára Boruzs

PMC · DOI: 10.1371/journal.pone.0317034 · PLOS One · 2025-03-26

## TL;DR

This study explores how socio-demographic factors influence attitudes toward metformin and self-management barriers in Hungarian diabetes patients.

## Contribution

The study identifies specific socio-demographic influences on medication beliefs and environmental barriers in diabetes self-management.

## Key findings

- Patients with better financial status were more likely to feel the need to take metformin.
- Older age groups reported fewer concerns about metformin and more barriers to medication adherence.
- Education level and age significantly influenced perceptions of metformin's harm and barriers to exercise.

## Abstract

The key to effective patient care is the patient’s proper cooperation, so it is important to examine the beliefs about medicine and self-management among diabetes patients. Therefore, the primary aim of the study was to investigate the attitude toward metformin medication and self-management of adult patients with diabetes in Hungary. A total of 591 metformin-taking diabetes patients completed the Beliefs about Medicine Questionnaire, while 283 metformin-taking diabetes patients completed the Environmental Barrier Assessment Scale. Multivariate regression analysis was conducted to investigate which socio-demographic factors influence the beliefs regarding medicines and various environmental barriers to diabetes self-management. Participants who reported a good or very good financial status were more likely to feel the need to take metformin compared to those perceiving bad or very bad financial status (coef = 0.25; p = 0.020). Respondents between 55-64 years and those older than 65 were significantly less concerned about metformin than those aged 18-24 years (coef = -0.47; p = 0.028 and coef = -0.41; p = 0.047). Participants with secondary education were significantly less likely to think that metformin was harmful than those with primary education (coef = -0.50; p = 0.009). In addition, those aged 35 or older saw more barriers to taking medication than those aged 18-24 years (35-44: coef = -0.54; p = 0.020; 45-54: coef = -1.15; p < 0.001; 55-64: coef = -1.06; p < 0.001; 65 years or older: coef = -1.48; p < 0.001). Also, significant negative association was found for several factors (such as age, education, self-reported financial status, subjective health status) with barriers regarding exercise. Overall, socio-demographic factors significantly impact both the attitude toward medicine and diabetes self-management. However, the impact considerably varies according to different beliefs and environmental barriers. To further improve drug adherence and self-management for diabetes, doctors should take into consideration the relevant socio-demographic factors when communicating with their patients.

## Linked entities

- **Chemicals:** metformin (PubChem CID 4091)
- **Diseases:** diabetes mellitus (MONDO:0005015)

## Full-text entities

- **Diseases:** diabetes (MESH:D003920)
- **Chemicals:** metformin (MESH:D008687)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

47 references — full list in the complete paper: https://tomesphere.com/paper/PMC11940427/full.md

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Source: https://tomesphere.com/paper/PMC11940427