# Association between cognitive functioning and microbiota-gut-brain axis mediators in a memory clinic population

**Authors:** Claudio Singh Solorzano, Cristina Festari, Peppino Mirabelli, Elisa Mombelli, Luigi Coppola, Delia Luongo, Daniele Naviglio, Andrea Soricelli, Giulia Quattrini, Marco Salvatore, Michela Pievani, Annamaria Cattaneo, Giovanni B. Frisoni, Moira Marizzoni

PMC · DOI: 10.3389/fncel.2025.1550333 · 2025-03-12

## Full-text entities

- **Genes:** IL1B (interleukin 1 beta) [NCBI Gene 3553] {aka IL-1, IL1-BETA, IL1F2, IL1beta}, TNF (tumor necrosis factor) [NCBI Gene 7124] {aka DIF, IMD127, TNF-alpha, TNFA, TNFSF2, TNLG1F}, MAPT (microtubule associated protein tau) [NCBI Gene 4137] {aka DDPAC, FTD1, FTDP-17, MAPTL, MSTD, MTBT1}, TYR (tyrosinase) [NCBI Gene 7299] {aka ATN, CMM8, OCA1, OCA1A, OCAIA, SHEP3}, GFAP (glial fibrillary acidic protein) [NCBI Gene 2670] {aka ALXDRD}, NEFL (neurofilament light chain) [NCBI Gene 4747] {aka CMT1F, CMT2E, CMTDIG, NF-L, NF68, NFL}, IL18 (interleukin 18) [NCBI Gene 3606] {aka IGIF, IL-18, IL-1g, IL1F4}, HLA-G (major histocompatibility complex, class I, G) [NCBI Gene 3135] {aka MHC-G}, GAPDH (glyceraldehyde-3-phosphate dehydrogenase) [NCBI Gene 2597] {aka G3PD, GAPD, HEL-S-162eP}, IL10 (interleukin 10) [NCBI Gene 3586] {aka CSIF, GVHDS, IL-10, IL10A, TGIF}, POTEF (POTE ankyrin domain family member F) [NCBI Gene 728378] {aka A26C1B, POTE2alpha, POTEACTIN}
- **Diseases:** dementia (MESH:D003704), CI (MESH:D003072), frontotemporal lobar degeneration (MESH:D057174), vascular damage (MESH:D057772), neurocognitive disorders (MESH:D019965), CF (MESH:D003550), psychiatric disorders (MESH:D001523), endothelial damage (MESH:D014652), vascular dementias (MESH:D015140), NAD (MESH:D016111), AD (MESH:D000544), GM (MESH:C536735), neurodegeneration (MESH:D019636), Amyloid (MESH:C000718787), impairment of (MESH:D060825), neuroinflammation (MESH:D000090862), inflammation (MESH:D007249), major depression (MESH:D003865), astrogliosis (MESH:D005911), infection (MESH:D007239), endothelial (MESH:D005642)
- **Chemicals:** Acetonema (-), [18F]florbetapir (MESH:C545186), NAD (MESH:D009243), LPS (MESH:D008070), short-chain fatty acids (MESH:D005232)
- **Species:** Homo sapiens (human, species) [taxon 9606], Clostridia (class) [taxon 186801], Dialister (genus) [taxon 39948], Acetonema (genus) [taxon 2373], Eubacterium (genus) [taxon 1730], Collinsella (genus) [taxon 102106], Bifidobacterium (genus) [taxon 1678]

## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11936893/full.md

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Source: https://tomesphere.com/paper/PMC11936893