# Complementary Medicine Linked to a Significant Prostate-Specific Antigen (PSA) Reduction in a 61-Year-Old Man: A Case Report

**Authors:** Elizabeth Huang, Jake Wong, Theresa Rohr-Kirchgraber

PMC · DOI: 10.7759/cureus.79510 · 2025-02-23

## TL;DR

A 61-year-old man with advanced prostate cancer experienced a significant drop in PSA levels after using herbal medicine before starting standard treatment.

## Contribution

This case report suggests that traditional herbal medicine may serve as a complementary therapy for prostate cancer.

## Key findings

- Herbal medicine led to a 10-fold reduction in PSA levels over two months.
- Subsequent chemotherapy normalized PSA levels.
- The case highlights the potential of herbal medicine as a complementary treatment.

## Abstract

Medical treatment for metastatic prostate cancer (mPC) involves androgen deprivation therapy (ADT) and selective use of surgery, chemotherapy, and/or radiation therapy. Our 61-year-old Chinese man with mPC had a prostate-specific antigen (PSA) drop of over 100 ng/mL with herbal medicine. Presenting atypically with a supraclavicular mass and an initial PSA greater than 20 times the upper normal limit, he self-medicated with herbs while pending insurance approval of prescribed ADT. After two months, his PSA dropped 10-fold. Subsequent chemotherapy dropped his PSA to within the normal range. This highlights the potential of traditional herbal medicine to benefit patients and provide complementary therapy to established drug regimens.

## Linked entities

- **Diseases:** metastatic prostate cancer (MONDO:0004956)

## Full-text entities

- **Genes:** KLK3 (kallikrein related peptidase 3) [NCBI Gene 354] {aka APS, KLK2A1, PSA, hK3}
- **Diseases:** mPC (MESH:D011471)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11936307/full.md

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Source: https://tomesphere.com/paper/PMC11936307