# A Rare Case of Plasmacytoma Presenting as Pulmonary Mass

**Authors:** Qiang‐zhong Pi, Hu Luo

PMC · DOI: 10.1002/rcr2.70168 · 2025-03-25

## TL;DR

A rare case of plasmacytoma appearing as a lung mass was effectively treated with radiotherapy and chemotherapy.

## Contribution

This case highlights an exceptional treatment response in a rare plasmacytoma presentation.

## Key findings

- Plasmacytoma can be diagnosed using bone scans, CT-guided biopsy, and bone marrow biopsy.
- The patient showed an exceptional response to radiotherapy and proteasome inhibitor-based chemotherapy.
- The case involved multiple myeloma with extramedullary plasmacytoma.

## Abstract

Plasmacytoma can manifest as a solitary pulmonary mass, which can be accurately diagnosed through a combination of Bone scan, serum protein electrophoresis, computed tomography (CT)‐guided biopsy and bone marrow biopsy. Notably, this case diagnosed with multiple myeloma (MM) with extramedullary plasmacytoma (EMP) demonstrated an exceptional treatment response to radiotherapy and proteasome inhibitor–based chemotherapy.

We report a patient diagnosed with multiple myeloma (MM) with extramedullary plasmacytoma (EMP) who demonstrated an exceptional treatment response to radiotherapy and proteasome inhibitor–based chemotherapy.

## Linked entities

- **Diseases:** plasmacytoma (MONDO:0005615), multiple myeloma (MONDO:0009693), extramedullary plasmacytoma (MONDO:0002754)

## Full-text entities

- **Diseases:** MM (MESH:D009101), EMP (MESH:C537514), Plasmacytoma (MESH:D010954), Pulmonary Mass. (MESH:C536030)

## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11934291/full.md

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Source: https://tomesphere.com/paper/PMC11934291