# Wolff‐Parkinson‐White Mimicking Posterior STEMI: When Even AI Gets It Wrong

**Authors:** Marco Biasin, Lorenzo Bonadiman, Francesca Vassanelli, Flavio Ribichini

PMC · DOI: 10.1002/ccr3.70363 · 2025-03-24

## TL;DR

This paper discusses a case where a heart condition mimicked a heart attack, showing the need for careful diagnosis even with AI help.

## Contribution

The paper emphasizes the importance of combining clinical evaluation with AI-assisted ECG analysis to avoid misdiagnosis in WPW cases.

## Key findings

- WPW can mimic ischemic ECG patterns, leading to potential misdiagnosis of acute coronary syndromes.
- Integrating clinical evaluation, echocardiography, and troponin testing improves diagnostic accuracy.
- AI-assisted ECG analysis alone may not be sufficient for accurate differentiation from true ischemia.

## Abstract

Wolff‐Parkinson‐White (WPW) can mimic ischemic ECG patterns, leading to potential misdiagnosis of acute coronary syndromes. This case highlights the importance of integrating clinical evaluation, echocardiography, and troponin testing with AI‐assisted ECG analysis to accurately differentiate pre‐excitation from true ischemia and avoid inappropriate interventions.

## Linked entities

- **Diseases:** acute coronary syndromes (MONDO:0005542)

## Full-text entities

- **Diseases:** acute coronary syndromes (MESH:D054058), ischemic (MESH:D002545), WPW (MESH:D014927), Posterior STEMI (MESH:D000072657), ischemia (MESH:D007511)

## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11933439/full.md

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Source: https://tomesphere.com/paper/PMC11933439