# Expanding Horizons: Increasing Injectable Vaccine in the Expanded Program on Immunization

**Authors:** Birendra Prasad Gupta, Namita Ghimire

PMC · DOI: 10.31729/jnma.8773 · JNMA: Journal of the Nepal Medical Association · 2024-11-30

## TL;DR

This paper discusses the expansion of childhood vaccines and the need for fewer injections through new delivery methods like oral or nasal vaccines.

## Contribution

The paper emphasizes the need for combined vaccines and alternative delivery methods to reduce injection burden and improve vaccine acceptance.

## Key findings

- The Expanded Program on Immunization now includes 11 antigens in 21 vaccines, up from 6 antigens in 1974.
- Multiple injections raise concerns about pain, adverse reactions, and vaccine acceptability.
- Alternative vaccine delivery methods could reduce injection burden and improve community acceptance.

## Abstract

The World Health Organization started the Expanded Program on Immunization in 1974, including 6 antigens with up to 8 vaccine doses for childhood vaccination. The number of antigens has now increased to 11 antigens in 21 vaccines. The expansion of vaccination programs to include more antigens and doses has led to concerns about the burden of multiple injections on infants and children, as well as factors such as fear of adverse reactions, pain, and overall acceptability of vaccines. To address these challenges, there's a call for research to focus on developing combined vaccines that can be administered through more acceptable routes, such as oral, nasal, or needleless administration. This approach could potentially reduce the number of injections required and increase the willingness of individuals to receive vaccines. We highlight the importance of ongoing research and innovation in vaccine development and delivery methods to ensure that vaccination programs remain effective, efficient, and acceptable to the communities they serve, particularly in resource-limited settings.

## Full-text entities

- **Diseases:** pain (MESH:D010146)

## Full text

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## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11931338/full.md

## References

19 references — full list in the complete paper: https://tomesphere.com/paper/PMC11931338/full.md

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Source: https://tomesphere.com/paper/PMC11931338