# Gastric inverted polyp successfully resected by underwater endoscopic mucosal resection

**Authors:** Yuki Nakamura, Takahiro Nomi, Sho Yasui, Jun‐ichi Okano, Ichiro Yamadori, Hidetaka Yamamoto, Yuichiro Sasaki, Hajime Isomoto

PMC · DOI: 10.1002/deo2.70103 · DEN Open · 2025-03-23

## TL;DR

A gastric inverted polyp was successfully removed using underwater endoscopic mucosal resection after growing over 11 years.

## Contribution

Demonstrates successful use of underwater endoscopic mucosal resection for resecting a gastric inverted polyp.

## Key findings

- The lesion was confirmed as a gastric inverted polyp through histopathological examination.
- Underwater endoscopic mucosal resection enabled complete en bloc resection for diagnosis and treatment.
- Gastric inverted polyps with central depression may have malignant potential and require endoscopic resection.

## Abstract

A 47‐year‐old man, who underwent an annual esophagogastroduodenoscopy as part of his routine check‐up, was found to have a small subepithelial lesion on the posterior wall of the gastric body in 2013. The lesion gradually increased in size during follow‐up. In 2024, 11 years after the initial detection, the lesion had grown to over 10 mm in diameter and exhibited central erythematous depression. Endoscopic ultrasonography was performed, revealing that the lesion originated from the second layer with uniformly low internal echogenicity. A biopsy suggested the possibility of a benign stromal tumor, but a definitive diagnosis was not achieved. To obtain a complete biopsy, en bloc resection was performed using underwater endoscopic mucosal resection. Histopathological examination confirmed the diagnosis of a gastric inverted polyp. Since gastric inverted polyps with central depression or erosion have the potential for malignancy, endoscopic resection is recommended.

## Full-text entities

- **Diseases:** malignancy (MESH:D009369), Gastric inverted polyp (MESH:D011127), stromal tumor (MESH:D046152), depression (MESH:D003866)

## Full text

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## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11931080/full.md

## References

9 references — full list in the complete paper: https://tomesphere.com/paper/PMC11931080/full.md

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Source: https://tomesphere.com/paper/PMC11931080