# A Case of Hypoglycemia Associated With Anorexia Nervosa Revealing Isolated Adrenocorticotropic Hormone (ACTH) Deficiency

## TL;DR

A patient with anorexia nervosa developed hypoglycemia due to a rare condition called isolated ACTH deficiency, highlighting the need to consider this diagnosis in similar cases.

## Contribution

The paper reports a rare case of isolated ACTH deficiency presenting with hypoglycemia in a patient with anorexia nervosa.

## Key findings

- The patient with anorexia nervosa was found to have isolated ACTH deficiency.
- Hypoglycemia in anorexia nervosa patients may indicate underlying adrenal insufficiency.
- This case emphasizes the importance of considering ACTH deficiency in the differential diagnosis of hypoglycemia in anorexia nervosa.

## Abstract

Anorexia nervosa (AN) typically affects young women and leads to severe emaciation, while isolated adrenocorticotropic hormone (ACTH) deficiency (IAD) usually occurs in middle-aged and older adults, causing secondary adrenal insufficiency, appetite loss, and weight loss. Although differentiating between these conditions can be challenging, their coexistence is rare. We encountered a patient with AN hospitalized for impaired consciousness due to hypoglycemia, who was later diagnosed with IAD. It is important to consider IAD as a differential diagnosis when hypoglycemia occurs in patients with AN.