# Pediatric epididymal schistosomiasis, challenging diagnosis, and implications

**Authors:** Juliana Arenas Hoyos, Jeff Lawrence Pugach, Lynne M. Eger, Sandy Cope-Yokoyama, Shane F. Batie

PMC · DOI: 10.1016/j.eucr.2025.102997 · Urology Case Reports · 2025-03-02

## TL;DR

This paper reports the first case of epididymal schistosomiasis in a U.S. pediatric patient, highlighting diagnostic challenges and the need for histology and thorough patient history.

## Contribution

The first documented case of pediatric epididymal schistosomiasis in the United States.

## Key findings

- Pediatric epididymal schistosomiasis is rare and requires histologic confirmation for diagnosis.
- A detailed patient history is crucial to identify potential exposure to endemic regions.
- Follow-up data on systemic sequelae in such cases remains limited.

## Abstract

Schistosomiasis is a parasitic infection that may be difficult to diagnose in non-endemic regions and may manifest with epididymal involvement.

Testicular schistosomiasis remains a rare disease. The diagnosis is based on clinical suspicion due to a low degree of specificity when it comes to laboratory tests and imaging studies. Treatment mainstays are anthelminthic medication and excision.

We present the first report of epididymal schistosomiasis in a pediatric patient in the United States. Patients require a definitive histologic diagnosis. It is helpful to obtain a thorough history to elucidate exposure to endemic areas as part of assessment and treatment.

•Schistosomiasis (SM) is rare parasitic infection that can present rarely as a pseudotumor of the testes or epididymis.•Histology is needed for diagnosis.•Organ sparing surgery may be considered if no involvement is clinically suspected.•There is scarce information regarding follow-up for systemic sequelae in these cases.

Schistosomiasis (SM) is rare parasitic infection that can present rarely as a pseudotumor of the testes or epididymis.

Histology is needed for diagnosis.

Organ sparing surgery may be considered if no involvement is clinically suspected.

There is scarce information regarding follow-up for systemic sequelae in these cases.

## Linked entities

- **Diseases:** schistosomiasis (MONDO:0015254)

## Full-text entities

- **Diseases:** parasitic infection (MESH:D010272), epididymal schistosomiasis (MESH:D004823), Schistosomiasis (MESH:D012552)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11930698/full.md

## References

16 references — full list in the complete paper: https://tomesphere.com/paper/PMC11930698/full.md

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Source: https://tomesphere.com/paper/PMC11930698