# Overcoming the Challenges of Intravenous Immunoglobulin Resistance in Kawasaki Disease: A Case Report

## TL;DR

This case report discusses a rare vasculitis in a 3-month-old infant who did not respond to initial immunoglobulin treatment.

## Contribution

The report highlights the challenges of managing immunoglobulin-resistant Kawasaki disease in infants.

## Key findings

- A 3-month-old infant showed no response to the first dose of intravenous immunoglobulin.
- The case emphasizes the need for advanced clinical evaluation and management at tertiary hospitals.
- The patient exhibited symptoms including fever, rash, and coronary artery dilatation.

## Abstract

Kawasaki disease, extremely rare vasculitis of unknown etiology characterized by inflammation of small to medium sized arteries of multiple systems. This case report enhances the knowledge and management skills of rare clinical conditions. Here we report a case of a 3-month-old infant presented with acute onset fever, rash, non-exudative conjunctivitis and swellings of hands and legs with blood culture positive sepsis and right coronary artery dilatation. The child didn't respond to treatment with the first dose of intravenous immunoglobulin. Therefore, the immunoglobulin resistant Kawasaki disease in infants needs further evaluation and clinical management at tertiary level hospitals.