# Panniculitis in Anti-MDA-5 Positive Juvenile Dermatomyositis: A Case Report

## TL;DR

A 17-year-old male with juvenile dermatomyositis developed rare panniculitis and was successfully treated with hydroxychloroquine and azathioprine.

## Contribution

This case report highlights the rare occurrence of panniculitis in anti-MDA5 positive juvenile dermatomyositis and its effective treatment strategy.

## Key findings

- Panniculitis occurred in a patient with anti-MDA5 positive juvenile dermatomyositis.
- Treatment with hydroxychloroquine and azathioprine controlled the lesions.
- Panniculitis is a rare manifestation in this condition.

## Abstract

Panniculitis is a rare clinical finding in dermatomyositis. There are few reported cases in the medical literature. In this report, we describe a 17-year-old male patient with anti-MDA5 positive hypomyopathic dermatomyositis who, eight months after diagnosis, presented with indurated nodules on the right forearm and right thigh despite methotrexate and monthly intravenous immunoglobulin treatment. A skin biopsy revealed lobular panniculitis with lymphocytic infiltrate. His lesions were successfully controlled with hydroxychloroquine and azathioprine. This article presents a case regarding the rarity of panniculitis in juvenile dermatomyositis and its treatment strategy.