# Trilogy of Fallot With a Large Right Atrial Thrombus: A Case Report

**Authors:** Ramachandra Barik, Debasis Acharya, Pranjit Deb, Debasis Panda, Sindhu Rao Malla

PMC · DOI: 10.7759/cureus.79395 · Cureus · 2025-02-21

## TL;DR

A young man with a rare heart condition and a large blood clot in his heart showed improvement after treatment with medication and a procedure to open his pulmonary valve.

## Contribution

This case report highlights the management of a rare congenital heart disease complicated by a large thrombus and neurological symptoms.

## Key findings

- The patient had Trilogy of Fallot with a large right atrial thrombus and a history of transient ischemic attacks.
- Treatment with low molecular weight heparin and balloon pulmonary valvotomy led to significant clinical improvement.

## Abstract

Trilogy of Fallot is a rare congenital heart disease consisting of pulmonary stenosis, right-to-left interatrial shunt, and right ventricular hypertrophy. It can lead to complications such as thrombus formation as a result of chronic hypoxia leading to erythrocytosis and hyperviscosity, and paradoxical embolisms due to the right-to-left interatrial shunt. This report illustrates a case of a young man who presented with cyanosis and right heart failure with a history of recurrent episodes of transient ischemic attacks. He was found to have Trilogy of Fallot with a large right atrial thrombus. He showed significant improvement following treatment with low molecular weight heparin and thereafter undergoing balloon pulmonary valvotomy.

## Linked entities

- **Diseases:** transient ischemic attacks (MONDO:0005264)

## Full-text entities

- **Diseases:** congenital heart disease (MESH:D006330), transient ischemic attacks (MESH:D002546), pulmonary stenosis (MESH:D011666), right ventricular hypertrophy (MESH:D017380), Trilogy of Fallot (MESH:D014286), erythrocytosis (MESH:D011086), embolisms (MESH:D004617), hypoxia (MESH:D000860), Atrial Thrombus (MESH:D013927), cyanosis (MESH:D003490), heart failure (MESH:D006333)
- **Chemicals:** heparin (MESH:D006493)

## Full text

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## Figures

7 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11929960/full.md

## References

12 references — full list in the complete paper: https://tomesphere.com/paper/PMC11929960/full.md

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Source: https://tomesphere.com/paper/PMC11929960