# Pulmonary Hypertension and Downhill Varices: An Incidental Finding

**Authors:** Bianca Thakkar, Teresa Da Cunha, Rachael Hagen, Roopjeet Bath

PMC · DOI: 10.7759/cureus.79385 · Cureus · 2025-02-20

## TL;DR

This paper reports a rare case of downhill varices caused by severe pulmonary hypertension, highlighting the need for individualized diagnosis and treatment.

## Contribution

The paper presents a novel case linking downhill varices to pulmonary hypertension without SVC obstruction.

## Key findings

- Downhill varices were found in a patient with severe pulmonary hypertension and no SVC obstruction.
- Severe pulmonary hypertension was identified as the probable cause of the varices via increased venous pressure.
- The patient's anemia improved with supportive care and no further bleeding occurred.

## Abstract

Downhill varices (DV), rare proximal esophageal varices, are typically associated with superior vena cava (SVC) obstruction. We present the case of an 80-year-old male with severe pulmonary hypertension and chronic obstructive pulmonary disease who presented with shortness of breath upon exertion along with new melena and anemia (hemoglobin 5.9 g/dL). Upper endoscopy revealed non-bleeding DV in the proximal esophagus and a vascular lesion on the tongue, with imaging and venography excluding SVC obstruction. Severe pulmonary hypertension was identified via transthoracic echocardiogram (TTE) and right heart catheterization (RHC) as the probable cause of DV via venous backflow and increased central venous pressure. The patient’s anemia improved with supportive care, and no further gastrointestinal bleeding occurred. Management involves identifying and addressing the underlying cause, with endoscopic intervention reserved for active bleeding. This case highlights the importance of recognizing DV as a potential complication of pulmonary hypertension and underscores the need for individualized diagnostic and therapeutic approaches.

## Linked entities

- **Diseases:** pulmonary hypertension (MONDO:0005149), chronic obstructive pulmonary disease (MONDO:0005002), anemia (MONDO:0002280)

## Full-text entities

- **Diseases:** SVC obstruction (MESH:D013479), vascular lesion (MESH:D014652), esophageal varices (MESH:D004932), bleeding (MESH:D006470), anemia (MESH:D000740), gastrointestinal bleeding (MESH:D006471), shortness of breath (MESH:D004417), melena (MESH:D008551), Pulmonary Hypertension (MESH:D006976), DV (MESH:D014648), chronic obstructive pulmonary disease (MESH:D029424)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11929598/full.md

## References

10 references — full list in the complete paper: https://tomesphere.com/paper/PMC11929598/full.md

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Source: https://tomesphere.com/paper/PMC11929598