# Distal Leg Posterior Tibial Nerve Schwannomas Combined With Tarsal Tunnel Syndrome: A Case Series and Literature Review

**Authors:** Gabriel Verly, Marcus André Acioly

PMC · DOI: 10.7759/cureus.79356 · Cureus · 2025-02-20

## TL;DR

This paper reports three rare cases where leg nerve tumors caused symptoms similar to tarsal tunnel syndrome, highlighting the importance of proper diagnosis and combined surgical approaches for effective treatment.

## Contribution

The study presents a novel case series linking posterior tibial nerve schwannomas with tarsal tunnel syndrome symptoms, emphasizing combined surgical strategies.

## Key findings

- Three patients with PTN schwannomas presented with TTS-like symptoms and were treated with tumor resection and tarsal tunnel decompression.
- Complete or partial pain resolution was achieved in all patients following surgery.
- Combined surgical approaches are recommended for managing schwannomas mimicking TTS.

## Abstract

While the pathophysiology of space-occupying lesions inside the tarsal tunnel causing tarsal tunnel syndrome (TTS) is obvious, the occurrence of a posterior tibial nerve (PTN) mass outside the tarsal tunnel but mimicking or in combination with TTS symptomatology is less clear. Therefore, we report three rare cases of patients presenting with TTS symptoms combined with a distal leg PTN schwannoma, all of whom were treated with tumor resection and tarsal tunnel decompression. All patients had a long-lasting history of leg and ankle pain radiating to the medial aspect of the foot and toes. Pain was especially worsened at night, during walking, and with weight bearing. PTN schwannomas were located at the distal third of the leg. One patient was secondarily decompressed after previous tumor resection elsewhere. The surgical approach included tumor resection with fascicle-sparing enucleation and tarsal tunnel decompression with single or two incisions. Tumor resection was complete in all patients, and the diagnosis of schwannomas was confirmed by histological analysis. Transient-sensitive deterioration was documented in one patient, but there were no motor complications. The pain was resolved completely in two patients and partially in one patient at the last follow-up. PTN schwannomas mimicking or in combination with TTS make the diagnosis challenging since they share most of the clinical symptoms and signs. Such recognition is of utmost importance for better patient management. In these situations, tarsal tunnel decompression could be included in the surgical procedure to achieve long-lasting relief of pain.

## Linked entities

- **Diseases:** tarsal tunnel syndrome (MONDO:0006994)

## Full-text entities

- **Diseases:** schwannomas (MESH:D009442), TTS (MESH:D013641), Tumor (MESH:D009369), Distal Leg Posterior Tibial Nerve Schwannomas (MESH:D020429), Pain (MESH:D010146)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11929371/full.md

## References

18 references — full list in the complete paper: https://tomesphere.com/paper/PMC11929371/full.md

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Source: https://tomesphere.com/paper/PMC11929371