# First person – Joshua Ginzel

PMC · DOI: 10.1242/dmm.052337 · 2025-03-19

## TL;DR

This paper explores how cancer progresses during its hidden early stages, contributing to its deadly nature.

## Contribution

The study reveals nonlinear progression patterns during the occult phase of cancer, offering new insights into cancer lethality.

## Key findings

- Cancer progression during the occult phase is nonlinear and contributes to its lethality.
- Systems biology approaches in mouse models help understand cancer initiation and progression.
- The research highlights the importance of studying early, hidden cancer stages.

## Abstract

First Person is a series of interviews with the first authors of a selection of papers published in Disease Models & Mechanisms, helping researchers promote themselves alongside their papers. Joshua Ginzel is first author on ‘
Nonlinear progression during the occult transition establishes cancer lethality’, published in DMM. Joshua is a PhD student in the lab of Joshua Snyder at Duke University, Durham, NC, USA, investigating cancer initiation and progression using systems biology approaches in mouse models.

## Linked entities

- **Diseases:** cancer (MONDO:0004992)
- **Species:** Mus musculus (taxon 10090)

## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11928059/full.md

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Source: https://tomesphere.com/paper/PMC11928059