Percutaneous transluminal angioplasty with stenting for the treatment of lower limb arteriosclerosis obliterans

TL;DR

This study shows that adding stents during angioplasty improves treatment outcomes for patients with leg artery disease.

Contribution

The study provides empirical evidence that PTAS is more effective than PTA alone for lower limb arteriosclerosis obliterans.

Findings

PTAS had a higher total effectiveness rate (95.83%) compared to PTA (83.33%).

PTAS resulted in better improvements in ABI, claudication distance, and SF-36 scores.

PTAS had a lower target lesion revascularization rate than PTA.

Abstract

With the advancement of minimally invasive techniques, percutaneous transluminal angioplasty with stenting (PTAS) has emerged as a significant treatment approach for lower limb arteriosclerosis obliterans (ASO)

The aim of this study was to evaluate the clinical efficacy of PTAS in patients with lower limb ASO.

A total of 96 ASO patients admitted to our hospital between January 2021 and December 2022 were included in this study. They were divided into 2 groups according to the treatment method: the observation group (n = 48) received PTAS treatment, while the control group (n = 48) underwent percutaneous transluminal angioplasty (PTA). Treatment efficacy was evaluated 30 dayspostsurgery. Pre- and postoperative measurements included the ankle-brachial index (ABI), claudication distance, and quality of life scores derived from the 36-Item Short Form Health Survey (SF-36).

Postoperative complications and the rate of target lesion revascularization (TLR) were also recorded.

In the observation group, 29 patients experienced marked improvement and 17 were effectively treated, yielding the total effectiveness rate of 95.83%, which was higher than in the control group (83.33%; P = 0.045). Both groups showed significant improvement in ABI, claudication distance, and SF-36 scores after treatment, with the observation group presenting significantly better results than the control group. There was no difference in the total incidence of complications between the 2 groups (P = 0.24), however, the TLR occurrence rate was lower in the observation group (P = 0.04).

This study highlights the significant benefits of PTAS in the treatment of ASO, including improved overall effectiveness, enhanced functional indicators, and reduced rate of TLR, thus providing strong evidence for clinicians when selecting treatment methods for patients with lower limb ASO.