# Achieving Over 30% Body Weight Loss With Semaglutide in a Patient: A Case Report

**Authors:** Sidra Danish, Vallabh Dogra, Uzma Rauf, Maryam Saghir, Nadia Aslam

PMC · DOI: 10.7759/cureus.79254 · Cureus · 2025-02-18

## TL;DR

A 69-year-old woman with severe obesity lost over 30% of her body weight using semaglutide, improving her health significantly.

## Contribution

This case report demonstrates exceptional weight loss and health improvements with semaglutide in a patient with morbid obesity.

## Key findings

- The patient lost 90 lb (30% of her body weight) over 65 weeks with semaglutide.
- Her hypertension resolved and glucose levels normalized during treatment.
- The weight loss exceeded average results from previous studies.

## Abstract

A 69-year-old female with morbid obesity (BMI: 47) and hypertension achieved significant weight loss following treatment with semaglutide. Starting at 241 lb, she lost 90 lb (over 30% of her body weight) over 65 weeks without side effects. This weight loss exceeded the average reduction reported in previous studies. Additionally, her hypertension resolved, and her glucose levels normalized, illustrating the multifaceted benefits of semaglutide in weight management.

## Linked entities

- **Chemicals:** semaglutide (PubChem CID 56843331)
- **Diseases:** obesity (MONDO:0011122)

## Full-text entities

- **Diseases:** hypertension (MESH:D006973), Body Weight Loss (MESH:D001835), weight loss (MESH:D015431), obesity (MESH:D009765)
- **Chemicals:** glucose (MESH:D005947)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

8 references — full list in the complete paper: https://tomesphere.com/paper/PMC11925721/full.md

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Source: https://tomesphere.com/paper/PMC11925721