# Medication-Related Osteonecrosis Successfully Treated With Hyperbaric Oxygen Therapy and Conservative Treatment: A Case Report

## TL;DR

An elderly patient with severe jaw bone disease was successfully treated using hyperbaric oxygen and non-invasive methods instead of surgery.

## Contribution

Demonstrates successful conservative treatment of extensive MRONJ using hyperbaric oxygen therapy.

## Key findings

- Hyperbaric oxygen therapy combined with conservative treatment resolved extensive MRONJ in an elderly patient.
- Avoiding surgery reduced patient burden while achieving successful outcomes.
- Conservative treatment can be effective for MRONJ in patients with comorbid conditions.

## Abstract

Medication-related osteonecrosis of the jaws (MRONJ) is a major side effect of the antiresorptive drugs used in treating patients with osteoporosis and cancer. MRONJ appears as prolonged inflammation affecting the maxilla or mandible, with necrotic bone exposure and intraoral and extraoral fistulas. According to previous studies, surgery for this condition is highly beneficial. However, extensive surgical treatment generally overburdens patients with MRONJ, who often already suffer from other diseases such as cancer; therefore, further consideration must be given to their overall condition. Herein, we present the case of an elderly patient with extensive MRONJ who was successfully treated with hyperbaric oxygen therapy and conservative treatment.