# Arthritis with chronic pancreatitis—do not forget pancreatitis, panniculitis and polyarthritis (PPP) syndrome

## TL;DR

A rare syndrome called PPP, involving pancreatitis, arthritis, and skin inflammation, was identified in a child with chronic pancreatitis and joint pain.

## Contribution

The paper presents a case highlighting PPP syndrome as a potential cause of arthritis in children with chronic pancreatitis.

## Key findings

- PPP syndrome was suspected in a 3-year-old with chronic pancreatitis and knee pain after ruling out other causes.
- Treating chronic pancreatitis with NSAIDs improved the child's joint symptoms.
- PPP syndrome should be considered in patients with pancreatitis and unexplained arthritis.

## Abstract

Pancreatitis panniculitis and polyarthritis syndrome (PPP) syndrome is a rare complication of existing pancreatic disorders which include a triad of pancreatitis, oligo or monoarthritis and lobular panniculitis. We describe a case of a 3-year-old female child who presented with chronic pancreatitis and later developed knee pain during hospitalization. Other causes of arthritis were ruled out and pancreatitis-related arthritis, PPP syndrome was suspected. PPP syndrome treatment primarily involves managing the underlying pancreatic cause. In our case, managing the chronic pancreatitis with NSAIDs significantly improved the joint involvement.