# Lymphoepithelial cyst of the pancreatic tail: a rare entity with surgical and histopathological insights

**Authors:** William T Rumble, Priscilla Martin

PMC · DOI: 10.1093/jscr/rjaf186 · Journal of Surgical Case Reports · 2025-03-20

## TL;DR

This paper presents a rare case of a benign pancreatic cyst and highlights the challenges in diagnosing and managing such lesions.

## Contribution

The paper contributes a detailed case report and review of lymphoepithelial cysts, emphasizing surgical and histopathological insights.

## Key findings

- Lymphoepithelial cysts are rare and often misdiagnosed as more serious pancreatic lesions.
- Surgical resection and histopathological analysis are crucial for definitive diagnosis and management.
- A tailored surgical approach is recommended for treating these rare benign lesions.

## Abstract

Lymphoepithelial cysts (LECs) of the pancreas are rare, benign lesions often discovered incidentally during imaging for unrelated conditions. Their radiological features frequently overlap with those of other more common pancreatic cystic lesions, presenting a diagnostic challenge. In this report from a general surgical department on the Australia, we detail the assessment and management of a 54-year-old male with an enlarging pancreatic tail lesion initially thought to be a mucinous cystic neoplasm. Laparoscopic distal pancreatectomy and splenectomy was performed, and subsequent histopathological evaluation confirmed a benign LEC. This report reviews the literature base, clinical presentation, radiological findings, surgical approach, and pathological diagnosis of this rare condition. We emphasize the importance of a tailored approach to management and the role of surgery in definitive treatment.

## Linked entities

- **Diseases:** mucinous cystic neoplasm (MONDO:0044879)

## Full-text entities

- **Diseases:** pancreatic cystic lesions (MESH:D003550), mucinous cystic neoplasm (MESH:D018297), LECs (MESH:D003560), pancreatic tail lesion (MESH:D010182)

## Full text

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## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11924182/full.md

## References

14 references — full list in the complete paper: https://tomesphere.com/paper/PMC11924182/full.md

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Source: https://tomesphere.com/paper/PMC11924182