# Potential therapeutic mechanisms of Draconis Resina in cardiovascular diseases-a narrative review

## TL;DR

This review explores how Draconis Resina, a traditional Chinese medicine, may help treat cardiovascular diseases through various mechanisms.

## Contribution

The paper summarizes the potential therapeutic mechanisms of Draconis Resina in cardiovascular diseases.

## Key findings

- Draconis Resina may prevent thrombosis and reduce inflammation in cardiovascular diseases.
- It can alleviate oxidative stress and improve endothelial function.
- The herb may also mitigate myocardial fibrosis.

## Abstract

As a traditional Chinese herbal medicine, Draconis Resina (DR) has garnered significant attention due to its efficacy in treating various clinical diseases. Notably, it demonstrates remarkable therapeutic effects in cardiovascular diseases, such as atherosclerosis, coronary heart disease, and myocardial ischemia-reperfusion injury. A comprehensive understanding of the potential therapeutic mechanisms of DR in cardiovascular diseases can positively influence their prevention and treatment. Therefore, through a thorough literature review, this paper summarizes the primary mechanisms of DR in managing cardiovascular diseases, which include the prevention of thrombosis, inhibition of inflammatory responses, alleviation of oxidative stress, enhancement of endothelial function, and mitigation of myocardial fibrosis. There may remain many untapped therapeutic applications of DR that need further exploration. This review aims to give readers a deeper understanding of the DR and offer new perspectives.

Mechanisms of Draconis Resina’s Protection Effects in Cardiovascular Diseases. (NF-κB: Nuclear factor-κB; ROS: Reactive oxygen species; MDA: Malondialdehyde; SOD: Superoxide dismutase; LDH: Lactate Dehydrogenase; MCP-1: Monocyte chemotactic protein - 1; ICAM-1: Intercellular adhesion molecule - 1; VCAM-1: Vascular cell adhesion molecule - 1).

Mechanisms of Draconis Resina’s Protection Effects in Cardiovascular Diseases. (NF-κB: Nuclear factor-κB; ROS: Reactive oxygen species; MDA: Malondialdehyde; SOD: Superoxide dismutase; LDH: Lactate Dehydrogenase; MCP-1: Monocyte chemotactic protein - 1; ICAM-1: Intercellular adhesion molecule - 1; VCAM-1: Vascular cell adhesion molecule - 1).