# Clinical aspects of human mpox cases in the global scenario: an integrative review

## TL;DR

This paper reviews clinical aspects of human mpox cases globally, highlighting gaps in care guidance for healthcare teams.

## Contribution

The study compiles scientific evidence to guide multidisciplinary and nursing care for human mpox patients.

## Key findings

- The review identified 58 studies focusing on signs, symptoms, transmission, diagnosis, and prevention of mpox.
- Few studies specifically addressed care for multidisciplinary and nursing teams.
- The findings aim to improve patient management and prevent complications of MPXV infection.

## Abstract

In recent years, human-to-human transmission of MPXV has been frequently reported. Despite this, there is a lack of studies with strong evidence to guide the care practice focused on cases of human mpox.

To analyze scientific evidence in the literature that addresses clinical aspects related to cases of human mpox on the global scenario.

Integrative review conducted using five databases: SCOPUS, Web of Science, ScienceDirect, MEDLINE/PubMed and CINAHL. The last date of database access was October 3, 2024. The selection of studies and review report followed the recommendations of the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guideline.

With a sample of 58 studies, the main findings were aspects related to signs and symptoms, transmission, diagnosis, prevention and care for the multidisciplinary and nursing teams.

No studies were found that frequently and specifically addressed the care for the multidisciplinary team and, above all, the nursing team. Therefore, the results ofthis review mayfacilitate the management of patients with MPXV-related infections.

This study promoted the collection of scientific evidence that supports the care for patients with human mpox for the multidisciplinary team and the nursing team, which contributes to prevention, early detection and treatment of MPXV infection and its possible complications.