# Bing-Neel Syndrome: A Missed Opportunity

**Authors:** David R Drysdale, Mark E Gartner, Ryan A Smith, Bradley J Atoa, Aaron D Fleetwood, Tyson J Sjulin, Michael B Osswald

PMC · DOI: 10.7759/cureus.79144 · Cureus · 2025-02-17

## TL;DR

This paper presents a case of Bing-Neel syndrome misdiagnosed as COVID-19, emphasizing the need for early and accurate diagnosis.

## Contribution

The paper highlights the diagnostic challenges of Bing-Neel syndrome through a pathologically confirmed case.

## Key findings

- Bing-Neel syndrome was misdiagnosed as COVID-19 pneumonia and critical illness polyneuropathy.
- Early recognition of BNS is crucial for accurate diagnosis and treatment.

## Abstract

Bing-Neel syndrome (BNS) is a rare complication of Waldenström macroglobulinemia, characterized by lymphoplasmacytic lymphoma infiltration of the CNS. We present a pathologically confirmed case of BNS in a patient who was initially misdiagnosed with COVID-19 pneumonia and critical illness polyneuropathy. This case underscores the diagnostic challenges associated with BNS and highlights the importance of early recognition.

## Linked entities

- **Diseases:** Waldenström macroglobulinemia (MONDO:0100280), lymphoplasmacytic lymphoma (MONDO:0000432), critical illness polyneuropathy (MONDO:0001957)

## Full-text entities

- **Diseases:** lymphoplasmacytic lymphoma (MESH:D008223), critical illness polyneuropathy (MESH:D011115), Waldenstrom macroglobulinemia (MESH:D008258), COVID-19 pneumonia (MESH:D000086382), BNS (MESH:D002032)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC11921211/full.md

## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11921211/full.md

## References

14 references — full list in the complete paper: https://tomesphere.com/paper/PMC11921211/full.md

---
Source: https://tomesphere.com/paper/PMC11921211