# Seronegative Autoimmune Hepatitis Following Coronavirus Disease 2019 (COVID-19) Infection

## TL;DR

A patient developed autoimmune hepatitis after a COVID-19 infection, showing that the virus might trigger this condition.

## Contribution

This case report suggests a potential link between SARS-CoV-2 infection and seronegative autoimmune hepatitis.

## Key findings

- A 58-year-old patient had elevated liver enzymes after recovering from COVID-19.
- The patient was diagnosed with seronegative autoimmune hepatitis following a liver biopsy.
- The patient responded well to steroid treatment, supporting the diagnosis.

## Abstract

Autoimmune hepatitis is an autoimmune liver condition of uncertain etiology. Environmental triggers have been involved in the pathophysiology of the disease. The triggers include viruses, immunizations, and drugs. Since the emergence of the coronavirus disease 2019 (COVID-19) pandemic, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been implicated in the development of various autoimmune diseases. We report the case of a 58-year-old patient who had persistent elevation in liver transaminase levels after COVID-19 infection. After undergoing a liver biopsy, he was diagnosed with seronegative autoimmune hepatitis with an excellent response to steroids. Our case highlights the importance of considering the diagnosis of autoimmune hepatitis in patients with persistent elevation of liver transaminases after COVID-19 infection.