# Multi-beam multi-slice X-ray ptychography

**Authors:** Mattias Åstrand, Ulrich Vogt, Runqing Yang, Pablo Villanueva Perez, Tang Li, Mikhail Lyubomirskiy, Maik Kahnt

PMC · DOI: 10.1038/s41598-025-93757-0 · Scientific Reports · 2025-03-18

## TL;DR

This paper introduces a new X-ray imaging method that combines multi-beam and multi-slice ptychography to image larger and thicker samples with high resolution.

## Contribution

The novel integration of multi-beam and multi-slice ptychography enables high-resolution 3D imaging of larger, thicker samples.

## Key findings

- The combined method achieves high-resolution imaging of nanofeatures at depths comparable to lateral dimensions.
- The approach is robust and reproducible across different beamlines.
- This advancement establishes a new foundation for imaging larger and thicker samples.

## Abstract

X-ray ptychography provides the highest resolution non-destructive imaging at synchrotron radiation facilities, and the efficiency of this method is crucial for coping with limited experimental time. Recent advancements in multi-beam ptychography have enabled larger fields of view, but spatial resolution for large 3D samples remains constrained by their thickness, requiring consideration of multiple scattering events. Although this challenge has been addressed using multi-slicing in conventional ptychography, the integration of multi-slicing with multi-beam ptychography has not yet been explored. Here we present the first successful combination of these two methods, enabling high-resolution imaging of nanofeatures at depths comparable to the lateral dimensions that can be addressed by state-of-the-art multi-beam ptychography. Our approach is robust, reproducible across different beamlines, and ready for broader application. It marks a significant advancement in the field, establishing a new foundation for high-resolution 3D imaging of larger, thicker samples.

## Full-text entities

- **Genes:** Sobp (Sine oculis-binding protein) [NCBI Gene 36260] {aka CG8991, Dmel\CG8991, Sbp}
- **Chemicals:** Au (MESH:D006046), Kapton (-)

## Full text

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## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11920106/full.md

## References

7 references — full list in the complete paper: https://tomesphere.com/paper/PMC11920106/full.md

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Source: https://tomesphere.com/paper/PMC11920106