# Giant natal cleft epidermal inclusion cyst surgically excised in a young male in Australia

**Authors:** William Layt, Brielle Williams, Richard Maguire

PMC · DOI: 10.1093/jscr/rjaf141 · Journal of Surgical Case Reports · 2025-03-18

## TL;DR

A rare large epidermal cyst in a young man's natal cleft was successfully surgically removed after imaging confirmed its nature.

## Contribution

This case highlights the challenges of diagnosing and surgically managing giant epidermal inclusion cysts in atypical locations.

## Key findings

- A 7–8 cm epidermal inclusion cyst was diagnosed in the natal cleft using imaging techniques.
- Surgical excision with careful dissection led to an uneventful recovery.
- Pre-operative imaging and meticulous surgical technique are crucial for managing such cases.

## Abstract

Epidermal inclusion cysts are benign lesions commonly found in hair-bearing areas. Giant epidermal inclusion cysts (GEICs), those exceeding 5 cm in diameter, are rare and may pose diagnostic challenges, especially in atypical locations. We report the case of a 29-year-old male with a 7–8 cm swelling in the natal cleft, diagnosed as a GEIC after imaging studies, including ultrasound, CT, and MRI. Surgical excision was performed with careful dissection to preserve surrounding structures. The patient had an uneventful recovery. This case highlights the diagnostic and surgical challenges of GEICs in the natal cleft and emphasizes the importance of pre-operative imaging and meticulous surgical technique to avoid complications.

## Full-text entities

- **Diseases:** Epidermal inclusion cysts (MESH:D004814), swelling (MESH:D004487)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11915847/full.md

## References

8 references — full list in the complete paper: https://tomesphere.com/paper/PMC11915847/full.md

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Source: https://tomesphere.com/paper/PMC11915847