# Gene model for the ortholog of Pdk1 in Drosophila grimshawi

**Authors:** Megan E. Lawson, Madison A. Sharp, Laura K Reed, Norma Velazquez-Ulloa, Amy T. Hark, John Stanga, Chinmay P. Rele

PMC · DOI: 10.17912/micropub.biology.001042 · microPublication Biology · 2025-03-04

## TL;DR

This paper describes the gene model for the Pdk1 ortholog in Drosophila grimshawi, part of a study on the evolution of a key signaling pathway in fruit flies.

## Contribution

A new gene model for Pdk1 ortholog in Drosophila grimshawi is presented as part of an educational genomics dataset.

## Key findings

- The Pdk1 ortholog was identified in the Drosophila grimshawi genome assembly.
- The gene model contributes to a dataset for studying the evolution of the IIS pathway in Drosophila.
- The work follows a standardized gene annotation protocol for undergraduate research.

## Abstract

Gene model for the ortholog of Phosphoinositide-dependent kinase 1
(

Pdk1

) in the May 2011 (Agencourt dgri_caf1/DgriCAF1) Genome Assembly (GenBank Accession:
GCA_000005155.1
) of
Drosophila grimshawi
. This ortholog was characterized as part of a developing dataset to study the evolution of the Insulin/insulin-like growth factor signaling pathway (IIS) across the genus
Drosophila
using the Genomics Education Partnership gene annotation protocol for Course-based Undergraduate Research Experiences.

## Linked entities

- **Genes:** PDK1 (pyruvate dehydrogenase kinase 1) [NCBI Gene 5163]
- **Species:** Drosophila grimshawi (taxon 7222), Drosophila (taxon 7215)

## Full-text entities

- **Species:** Drosophila melanogaster (fruit fly, species) [taxon 7227]

## Full text

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## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC11915022/full.md

## References

26 references — full list in the complete paper: https://tomesphere.com/paper/PMC11915022/full.md

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Source: https://tomesphere.com/paper/PMC11915022