# Adult granulosa cell tumor with rare pulmonary presentation

**Authors:** Mark G. Evans, Anthony Crymes, Adam Bedeir, David R. Braxton, Matthew J. Oberley, Robert T. Muldoon

PMC · DOI: 10.1016/j.rmcr.2025.102185 · Respiratory Medicine Case Reports · 2025-02-26

## TL;DR

This paper reports a rare case of adult granulosa cell tumor originating in the lungs, expanding the known locations where this type of cancer can develop.

## Contribution

The paper presents a new case of primary thoracic adult granulosa cell tumor with pulmonary presentation.

## Key findings

- Adult granulosa cell tumor can present primarily in the lungs without pelvic involvement.
- Primary thoracic adult GCT expands the known anatomic origins of this cancer type.
- Such cases are associated with locoregional recurrence during treatment.

## Abstract

Adult granulosa cell tumor (GCT) is an uncommon sex cord-stromal neoplasm of the ovary. It typically demonstrates locoregional spread, and disease outside of the pelvis as metastasis is uncommon. Only a rare case of primary thoracic adult GCT has been documented, and here we describe another occurrence with unusual pulmonary presentation, thereby expanding the anatomic distribution across which adult GCT could potentially arise.

•Adult granulosa cell tumor (GCT) can demonstrate unusual primary pulmonary presentation with no evidence of pelvic disease.•Such rare cases are notable for locoregional recurrence during their treatment course.•This report of primary thoracic adult GCT expands the anatomic spectrum over which this cancer type is thought to originate.

Adult granulosa cell tumor (GCT) can demonstrate unusual primary pulmonary presentation with no evidence of pelvic disease.

Such rare cases are notable for locoregional recurrence during their treatment course.

This report of primary thoracic adult GCT expands the anatomic spectrum over which this cancer type is thought to originate.

## Full-text entities

- **Diseases:** GCT (MESH:D006106), sex cord-stromal neoplasm of the ovary (MESH:D010051)

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC11914798/full.md

## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11914798/full.md

## References

15 references — full list in the complete paper: https://tomesphere.com/paper/PMC11914798/full.md

---
Source: https://tomesphere.com/paper/PMC11914798