# Vitamin A concentration in bovine liver and milk does not only depend on characteristics of the farming system

**Authors:** Kirsten Schulz, Martin Bachmann, Jens Raila, Ruth Schmitt, Rudolf Staufenbiel, Heiko Scholz, Monika Wensch-Dorendorf, Sebastian Ptok, Anke Weissenborn, Robert Pieper

PMC · DOI: 10.1038/s41538-025-00397-9 · NPJ Science of Food · 2025-03-17

## TL;DR

This study found that vitamin A levels in cow liver and milk depend on factors like parity and pasture access, not just farming systems.

## Contribution

The study identifies parity and pasture availability as key factors influencing vitamin A and β-carotene levels in cows and milk.

## Key findings

- Multiparous cows had higher liver retinyl ester concentrations than primiparous cows.
- Pasture availability increased β-carotene concentrations in cows.
- Milk vitamin A levels rose with parity, but no deficiency or toxicity was observed.

## Abstract

The study examined the vitamin A status in commercially managed suckler cows and lactating dairy cows and identified primary influencing factors. Liver retinyl ester concentrations were higher in multiparous than primiparous cows (p < 0.01). Pasture availability was associated with higher β-carotene concentrations (p < 0.001). In dairy cows, pasture access during the dry period did not affect any of the parameters assayed. β-Carotene and retinol in milk increased with parity. No vitamin A deficiency or hypervitaminosis A was detected. Liver and milk retinol and retinyl ester concentrations that were analysed in the present study and data from a recent German total diet study were used to estimate the exposure to preformed vitamin A in vulnerable groups (children, 0.5–5 years). 95th percentiles of preformed vitamin A intake do not exceed tolerable upper intake levels in individuals between 1 year and 5 years, but in infants 6 to 12 months of age.

## Linked entities

- **Chemicals:** vitamin A (PubChem CID 445354), β-carotene (PubChem CID 573), retinol (PubChem CID 3840), retinyl ester (PubChem CID 5460164)
- **Species:** Bos taurus (taxon 9913)

## Full-text entities

- **Diseases:** vitamin A deficiency (MESH:D014802), hypervitaminosis A (MESH:D006986)
- **Chemicals:** beta-Carotene (MESH:D019207), retinyl ester (MESH:D000084562), Vitamin A (MESH:D014801)
- **Species:** Bos taurus (bovine, species) [taxon 9913]

## Full text

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## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11914524/full.md

## References

14 references — full list in the complete paper: https://tomesphere.com/paper/PMC11914524/full.md

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Source: https://tomesphere.com/paper/PMC11914524