# Endoscopic Transnasal Transclival Removal of a Giant Hemangiopericytoma Involving the Clivus and C1-C2 Vertebrae: A Clinical Case and Literature Review

**Authors:** Alexey N Shkarubo, Diana S Adueva, Dmitry N Andreev, Suzanne A Galstyan, Ilya V Chernov, Andrey A Panteleyev

PMC · DOI: 10.7759/cureus.79040 · 2025-02-15

## TL;DR

This paper presents a rare case of removing a large brain tumor through the nose and skull base, highlighting the importance of accurate diagnosis and radical treatment.

## Contribution

The paper describes a novel transnasal transclival approach for removing a giant hemangiopericytoma at the craniovertebral junction, not previously documented.

## Key findings

- Transnasal transclival subtotal removal was successfully used for a giant hemangiopericytoma at the C1-C2 level.
- Accurate diagnosis through instrumental and morphological examination is crucial for patient outcomes.
- Radical tumor removal followed by radiation therapy is essential for treating intracranial hemangiopericytomas.

## Abstract

Hemangiopericytomas, or solitary fibrous tumors (SFT), are neoplasms of mesenchymal origin that are quite rare in oncological practice. These tumors often grow to large sizes before the onset of clinical symptoms, and in imaging studies, they closely resemble meningiomas, making diagnosis challenging. When treating intracranial hemangiopericytoma, it is necessary to ensure the most radical removal followed by radiation therapy. We present a rare case of transnasal transclival subtotal removal of a giant hemangiopericytoma/SFT of the craniovertebral junction and the C1-C2 vertebral level, not previously described in the literature. Based on the results of the literature review, it was determined that an accurate diagnosis during the instrumental and morphological examination is crucial for the future outcome of a patient with intracranial hemangiopericytoma, as confirmed in the presented case.

## Linked entities

- **Diseases:** hemangiopericytoma (MONDO:0005094)

## Full-text entities

- **Diseases:** meningiomas (MESH:D008579), Hemangiopericytoma (MESH:D006393), neoplasms (MESH:D009369), SFT (MESH:D054364)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

6 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11912516/full.md

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Source: https://tomesphere.com/paper/PMC11912516