Mean total macular volume measurement using optical coherence tomography in already diagnosed primary open angle glaucoma patients

TL;DR

This study measured macular volume in glaucoma patients using OCT and found it to be reduced, suggesting it could help track the disease.

Contribution

The study provides empirical evidence of reduced macular volume in primary open angle glaucoma patients using OCT.

Findings

POAG patients had a mean total macular volume of 6.30 ± 1.09 mm³.

Reduced macular volume was observed and can be measured non-invasively with OCT.

MTMV loss is a useful indicator for documenting and monitoring glaucoma progression.

Abstract

To measure the mean total macular volume (MTMV) in primary open angle glaucoma (POAG) patients using optical coherence tomography (OCT).

This descriptive cross sectional study was carried out in the department of ophthalmology, Bahawal Victoria Hospital, Bahawalpur from October 2021 to April 2022. A total of 30 patients with POAG, of either gender, between the ages of 20-60 years were included. Patients with secondary glaucoma, having previous intraocular surgery, patients with history of trauma, patients with high myopia and macular disease were excluded. After taking systemic and ophthalmic history, examination of anterior and posterior segments was carried out including best corrected visual acuity (BCVA), intraocular pressure (IOP), central corneal thickness (CCT), gonioscopy, dilated fundus examination of optic nerve and retina, and 30-2° visual field (VF) analysis. OCT was carried out in each patient to measure RNFL thickness and MTMV.

Mean age in our study was 45.50 ± 8.20 years. Majority of these patients 22 (73.33%) were between 41-60 years of age. Among these 30 patients, 20 (66.67%) were male and 10 (33.33%) were females with a male to female ratio of 2:1. MTMV in these POAG patients using OCT was 6.30 ± 1.09 mm3.

Our study concluded that POAG patients have a reduced MTMV and it can be easily measuresd by a non-invasive technique using OCT. MTMV loss is a useful indicator of documenting glaucoma and monitoring its progression in POAG patients.

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