# Recurrent Idiopathic Thrombocytopenic Purpura Associated With Splenosis: A Case Report

**Authors:** Jose L Mejia, Luis Mejia Sierra

PMC · DOI: 10.7759/cureus.80622 · Cureus · 2025-03-15

## TL;DR

This case report describes a rare recurrence of a blood disorder after surgery, linked to leftover spleen tissue.

## Contribution

The report highlights splenosis as a potential cause of post-splenectomy recurrence in immune thrombocytopenic purpura.

## Key findings

- Recurrent immune thrombocytopenic purpura occurred years after splenectomy.
- Splenosis was identified as a possible cause of the recurrence.
- Reoperation led to improved disease management.

## Abstract

Immune thrombocytopenic purpura is a bleeding disorder in which the immune system develops antibodies against its cells, such as platelets, causing purpura and hemorrhagic episodes. The problem can be primary or idiopathic and secondary to other conditions, such as certain drugs and autoimmune conditions like lupus erythematosus. In children, spontaneous remissions are not uncommon, but they are rare in adults, in whom, after a period of medical treatment, splenectomy is necessary. Recurrence after surgery requires extensive workup, and although not quite common, remnants of the spleen or splenules should be suspected as one of the causes. The present case report relates to a recurrent disease episode several years after surgery, its management, and evolution after reoperation.

## Linked entities

- **Diseases:** lupus erythematosus (MONDO:0004670)

## Full-text entities

- **Diseases:** purpura (MESH:D011693), autoimmune conditions (MESH:D001327), Idiopathic Thrombocytopenic Purpura (MESH:D016553), lupus erythematosus (MESH:D008180), bleeding disorder (MESH:D006470), Splenosis (MESH:D017890)

## Full text

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## Figures

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## References

6 references — full list in the complete paper: https://tomesphere.com/paper/PMC11910191/full.md

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Source: https://tomesphere.com/paper/PMC11910191