# A Hidden Tumor: Unraveling a Gastrointestinal Stromal Tumor in a 44-Year-Old Male Patient With Epigastric Pain

**Authors:** Nika Harutyunyan

PMC · DOI: 10.7759/cureus.78953 · Cureus · 2025-02-13

## TL;DR

A 44-year-old man with persistent stomach pain and gastrointestinal symptoms was diagnosed with a rare tumor, highlighting the difficulty in diagnosing such cases.

## Contribution

This case report adds to the understanding of gastrointestinal stromal tumors (GISTs) with nonspecific symptoms and emphasizes the need for thorough evaluation.

## Key findings

- The patient's symptoms led to the discovery of a T3N0 gastrointestinal stromal tumor in the gastric antrum.
- Surgical intervention was successful, and the tumor's early stage suggests a favorable prognosis.
- The case highlights the importance of multidisciplinary care in managing complex gastrointestinal conditions.

## Abstract

This case report discusses a 44-year-old male who presented with recurrent epigastric pain after starting Ozempic for weight management, which persisted despite switching to Jardiance. His symptoms evolved into diarrhea and fever while vacationing in Mexico, with notable episodes of bloody stools and greasy, floaty stools upon return home. Despite normal laboratory tests and negative stool pathogen results, a CT scan revealed a mass in the gastric antrum. Subsequent endoscopy and fine-needle aspiration confirmed a gastrointestinal stromal tumor (GIST), classified as T3N0. The patient underwent laparoscopic distal gastrectomy with Billroth II gastrojejunostomy. This case underscores the challenge of diagnosing GISTs due to nonspecific gastrointestinal symptoms, emphasizing the necessity for thorough evaluation in persistent cases. The favorable prognosis associated with T3N0 classification highlights the importance of early identification and surgical intervention. Monitoring for recurrence and considering adjuvant therapy are essential in managing such tumors. This case illustrates the value of multidisciplinary care in addressing complex gastrointestinal conditions.

## Linked entities

- **Chemicals:** Ozempic (PubChem CID 56843331), Jardiance (PubChem CID 11949646)
- **Diseases:** gastrointestinal stromal tumor (MONDO:0011719)

## Full-text entities

- **Diseases:** diarrhea (MESH:D003967), fever (MESH:D005334), GIST (MESH:D046152), Epigastric Pain (MESH:D010146), Tumor (MESH:D009369)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11910190/full.md

## References

6 references — full list in the complete paper: https://tomesphere.com/paper/PMC11910190/full.md

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Source: https://tomesphere.com/paper/PMC11910190