# Kikuchi Disease in a Young Woman With Sickle Cell Disease: A Case Report

## TL;DR

A 15-year-old girl with sickle cell disease developed Kikuchi disease, a rare lymph node disorder, and was successfully treated with steroids and hydroxychloroquine.

## Contribution

This case highlights the rare co-occurrence of Kikuchi disease and sickle cell disease in a young patient.

## Key findings

- A 15-year-old girl with sickle cell disease presented with fever and lymphadenopathy.
- Kikuchi disease was confirmed via lymph node biopsy and successfully treated with steroids and hydroxychloroquine.
- The patient remained stable with no recurrence during follow-up.

## Abstract

Kikuchi-Fujimoto disease (KFD) is a rare, benign, and self-limiting disorder characterized by necrotizing lymphadenitis, primarily affecting young adults and adolescents. Its etiology and pathogenesis remain unclear and complex. Common presentations include constitutional symptoms such as lymphadenopathy and fever.

This study reports the case of a 15-year-old girl who presented with a fever of unknown origin and was found to have lymphadenopathy, which was associated with sickle cell disease (SCD). The diagnosis was confirmed through the pathological features of lymph node biopsy, with the patient successfully treated with steroids and hydroxychloroquine. She remained stable on follow-up, with no recurrence of fever or lymphadenopathy.