# Outcomes of drug provocation tests in children with chronic complications and comorbidities: Case series

**Authors:** Kouhei Hagino, Kiwako Yamamoto-Hanada, Seiko Hirai, Daisuke Harama, Marei Omori, Yasuaki Matsumoto, Daichi Suzuki, Kotaro Umezawa, Fumi Ishikawa, Kenji Toyokuni, Tatsuki Fukuie, Yukihiro Ohya

PMC · DOI: 10.1016/j.jacig.2025.100436 · The Journal of Allergy and Clinical Immunology: Global · 2025-02-03

## TL;DR

Drug provocation tests can safely and accurately diagnose drug allergies in children with chronic conditions.

## Contribution

The study shows drug provocation tests are feasible in children with underlying diseases.

## Key findings

- Drug provocation tests were conducted in children with chronic complications and comorbidities.
- The tests enabled accurate diagnosis of drug allergy in these children.

## Abstract

A study demonstrated that drug provocation tests could be conducted in children with underlying diseases, enabling accurate diagnosis of drug allergy. The study investigators hope that their work will allow more children with underlying conditions to undergo drug provocation tests.

## Full-text entities

- **Diseases:** drug allergy (MESH:D004342)

## Full text

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## References

10 references — full list in the complete paper: https://tomesphere.com/paper/PMC11909742/full.md

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Source: https://tomesphere.com/paper/PMC11909742