# Osteomesopyknosis: A Bone-Sclerosing Disorder that May be Confused with Bone Metastases

## TL;DR

This paper discusses osteomesopyknosis, a rare bone condition that can be mistaken for bone cancer, and presents a new case to improve its recognition.

## Contribution

The paper contributes a new case of osteomesopyknosis and a review of prior cases to aid in diagnosing this rare bone disorder.

## Key findings

- Osteomesopyknosis is a rare, likely genetic, sclerosing bone disorder.
- It can be mistaken for bone metastases due to similar imaging features.
- Reviewing cases helps improve recognition of this non-malignant condition.

## Abstract

Sclerosing bone disorders encompass a range of genetic and acquired diseases. The potential for bone metastases is often a significant concern, especially when multiple discrete lesions are present. Several non-malignant disorders can also produce similar patterns of bone abnormalities. Among these is osteomesopyknosis, a rare condition characterized by multiple sclerotic lesions in the axial skeleton. Only a few cases of this presumably genetic disease have been documented. In this report, we present a new case and review previously published cases to enhance understanding and facilitate recognition of this disorder within the broader category of sclerosing bone diseases.