# The Addition of Low‐Dose Lidocaine and Triamcinolone Reduces the Adverse Effects of 2‐Deoxycholate Injection Without Affecting the Long‐Term Results

## TL;DR

Adding low-dose lidocaine and triamcinolone to deoxycholic acid injections reduces pain and swelling without affecting fat reduction results.

## Contribution

Combining low-dose lidocaine and triamcinolone with deoxycholic acid improves patient comfort without compromising efficacy.

## Key findings

- The intervention group had significantly less pain and swelling compared to the control group.
- Both groups showed similar submental fat reduction, with the intervention group showing greater volumetric loss.
- The combination did not cause steroid-related side effects.

## Abstract

The study investigates the efficacy of combining low‐dose triamcinolone acetonide (TAC) and lidocaine with deoxycholic acid (DCA) injections to reduce adverse effects (AEs) without compromising long‐term results.

A double‐blind, randomized trial was conducted with 15 subjects, divided into a control group (DCA with lidocaine) and an intervention group (DCA with low‐dose TAC and lidocaine). The primary outcomes measured were injection pain, swelling, and submental fat reduction.

Results indicated that the intervention group experienced significantly reduced pain and swelling compared to the control group. Both groups showed similar efficacy in submental fat reduction, with the intervention group demonstrating a greater mean volumetric loss.

The study concludes that the addition of low‐dose TAC and lidocaine to DCA injections is a safe and effective method to enhance patient comfort and treatment outcomes without inducing steroid‐related side effects.