# Case report: Gouty renal abscess and gouty sacroiliitis associated with genetic variants of a young woman

## TL;DR

This case report describes a rare instance of gout in a young woman, involving kidney and joint complications linked to genetic factors.

## Contribution

The novelty lies in presenting a rare case of gout in a young woman with gouty sacroiliitis and nephropathy associated with genetic variants.

## Key findings

- A young woman presented with gouty sacroiliitis and gouty nephropathy.
- The case was associated with genetic susceptibility loci for gout.
- The report highlights the rare occurrence of gout in young women.

## Abstract

Gout is a form of inflammatory arthritis characterized by the deposition of monosodium urate (MSU) crystals in the joints, resulting from a disorder in purine metabolism. It occurs more frequently in men than in women prior to menopause and is rare in young women. Gout can lead to various health complications, with many patients experiencing a significant burden of chronic kidney disease (CKD) and joint deformities. The development of gout is influenced by a complex interplay of genetic, environmental, and lifestyle factors, with elevated serum MSU levels serving as a key risk factor for its onset. However, only 10% of individuals with hyperuricemia go on to develop clinical gout, and several susceptibility loci are associated with the condition. Here, we present a case of a young woman with gouty sacroiliitis and gouty nephropathy linked to susceptibility loci.