# Amoebic liver abscess: diagnosis and management of a single case in Guangdong, China

**Authors:** Yixin He, Dana Huang, Ying Yang

PMC · DOI: 10.1186/s12879-025-10623-0 · BMC Infectious Diseases · 2025-03-12

## TL;DR

This case report details the diagnosis and treatment of a 32-year-old man with amoebic liver abscess in China, highlighting the importance of early detection and proper treatment.

## Contribution

The paper presents a specific case of amoebic liver abscess in a non-endemic region, emphasizing diagnostic and management challenges.

## Key findings

- The patient showed improvement after abscess drainage and metronidazole treatment.
- Early diagnosis and timely intervention are critical for preventing complications and reducing mortality.
- Amoebic liver abscess remains a concern despite declining global incidence.

## Abstract

Amoebic liver abscess is a hepatic infection due to the invasion of Entamoeba histolytica. This parasitic infection is globally distributed, particularly in tropical and subtropical regions. A remarkable decline in the incidence of amoebic liver abscesses has been observed in recent years thanks to economic and public health progress.

This case report describes the symptoms of a 32-year-old male with an amoebic liver abscess. Despite the diagnostic difficulties encountered, favorable outcomes were obtained after the appropriate drainage of the abscess and the appropriate anti-amoebic therapy by the administration of metronidazole.

The management of amoebic liver abscess requires a meticulous evaluation of the patient’s clinical manifestations, the severity of the condition, and the response to therapeutic interventions. Early identification, combined with timely and effective treatment, is essential to reduce the risk of complications and the mortality rate.

Not applicable.

## Linked entities

- **Chemicals:** metronidazole (PubChem CID 4173)
- **Species:** Entamoeba histolytica (taxon 5759)

## Full-text entities

- **Diseases:** abscess (MESH:D000038), parasitic infection (MESH:D010272), hepatic infection (MESH:D056486), Amoebic liver abscess (MESH:D008101)
- **Chemicals:** metronidazole (MESH:D008795)
- **Species:** Entamoeba histolytica (species) [taxon 5759], Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11905540/full.md

## References

1 references — full list in the complete paper: https://tomesphere.com/paper/PMC11905540/full.md

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Source: https://tomesphere.com/paper/PMC11905540