# Evaluation of hyper-lipidaemia as a predictive marker for gestational diabetes among Indian women

**Authors:** Shivani Chitale, Sajaykumar Patil, Nitin S. Kshirsagar

PMC · DOI: 10.6026/9732063002001206 · Bioinformation · 2024-10-31

## TL;DR

The study finds that high lipid levels early in pregnancy may predict gestational diabetes in Indian women.

## Contribution

It identifies hyperlipidemia as a potential early predictor of gestational diabetes mellitus.

## Key findings

- Triglyceride, total cholesterol, and hyperlipidemia levels were significant predictors of GDM with p < 0.05.
- Early lipid screening may help identify women at risk for gestational diabetes.
- More research is needed to confirm these findings and their clinical relevance.

## Abstract

Gestational diabetes mellitus (GDM) is an impaired capacity to metabolize carbohydrates throughout pregnancy; its occurrence is
increasing in around 20-27% globally. Therefore, it is of interest to know the hyperlipidemia levels at 12-14 weeks with GDM. 100
patients were assessed using history, general, systemic, antenatal and routine examination along with follow-up at 20 weeks for Oral
Glucose Tolerance Test (OGTT). Data shows that triglyceride, total cholesterol and hyperlipidemia levels showed significant predictors
of development of GDM as the p value was <0.05. Although gestational diabetes mellitus is linked to surgical deliveries and foetal
problems such as macrosomia yet more studies are recommended to validate the data.

## Linked entities

- **Diseases:** Gestational diabetes mellitus (MONDO:0005406)

## Full-text entities

- **Diseases:** macrosomia (MESH:D005320), GDM (MESH:D016640), hyper-lipidaemia (MESH:D007589), hyperlipidemia (MESH:D006949)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## References

21 references — full list in the complete paper: https://tomesphere.com/paper/PMC11904173/full.md

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Source: https://tomesphere.com/paper/PMC11904173