# The role of extra-corporeal radiation therapy for osteo-sarcoma

## TL;DR

Extracorporeal radiation therapy is a new treatment for osteosarcoma that helps preserve limbs and reduce complications.

## Contribution

The paper reviews the effectiveness and clinical benefits of extracorporeal radiation therapy for osteosarcoma.

## Key findings

- ECRT helps preserve limb function and reduces recurrence risk in osteosarcoma patients.
- Promising local control and survival rates support the potential of ECRT as a treatment option.
- ECRT offers advantages over prosthetics or allografts by decreasing complications.

## Abstract

Extracorporeal radiation therapy is a new limb-salvaging procedure increasingly used, especially in situations where it may not be
possible to carry out complete surgical resection. Osteosarcoma is a malignant tumour of bone that, typically, presents in young people,
and often, it is managed by using different modes of treatment, which include surgery and chemotherapy. This therapy involves the removal
of the involved segment of bone, its extracorporeal irradiation, followed by re-implantation to preserve limb function and reduce the
risk of recurrence. Therefore, it is of interest to review the effectiveness of, clinical uses, and results of ECRT, focusing on its
benefits in terms of bony conservation and decreased complications with either prosthetics or allografts. Promising local control and
survival rates further cement its potential.